Prospects for the application of mathematical modeling in clinical medicine
Автор: Gaisenok Oleg V., Lituev Victor N.
Журнал: Cardiometry @cardiometry
Рубрика: Original research
Статья в выпуске: 14, 2019 года.
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Aims The aims of the study are to follow the correlation of СAD development with various clinical and laboratory parameters and risk factors in a cohort of patients with multiple medical conditions and evaluate the effect of various parameters in the development of the disease using a new mathematical model approach. Materials and methods This study covers a limited patient cohort (n = 12) formed according to the rules of a local register. We have applied the methods of probabilistic mathematical modeling of cardiovascular disease with the formation of an aggregated matrix. Matrix fields were presented the instrumental methods of diagnosis and clinical and biochemical blood tests of patients. Results When using various methods of mathematical and statistical analysis (including cluster and factor analysis), created has been a graphic model of interaction of clinical, biochemical and instrumental parameters with the development of CAD. The mathematical and statistical completeness of the description of the patient’s condition by the parameters of pathology on the basis of the measure of reliability of the completeness of the description was R=0,98-1,0, the coefficient of determination was equal to R2=92,0-98,0%...
Cad, risk factors, mathematical modeling, triggers, aggregated matrix
Короткий адрес: https://sciup.org/148308869
IDR: 148308869 | DOI: 10.12710/cardiometry.2019.14.6470
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