Original research. Рубрика в журнале - Cardiometry
A distributed e-health management model with edge computing in healthcare framework
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Edge healthcare system is recognized as an acceptable paradigm for resolving this problem. The IoMT is divided into two sub-networks - intraWBANs and beyond-WBANs - based on the physical bonds of WBANs. Given the features of the healthcare systems, medical emergency, AoI and power depreciation are the prices of MUs. Intra-WBANs, a cooperative game shapes the wireless channel resource allocation problem. The Nash negotiation solution is used to get the unique optimum point in Pareto. MUs are regarded reasonable and perhaps egoistic in non-WBANs. Another non-cooperative activity is therefore developed to reduce overall system costs. The assessments of the performance of the system-wide cost and of the number of MUs gaining from edge computer systems are done to illustrate the success of our solution. Finally, for further effort, numerous barriers to research and open questions are highlighted.
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A phenomenological study to understand gender diversity and inclusion in the tech industry
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Various researches have established that diversity with inclusion yields a competitive advantage and promotes innovation in workplaces. Gender diversity and retention of top women talent, however, remains a problem. This study explored the reasons leading to the lower representation of women in the tech industry and the impact of the diversity and inclusion initiatives on the lives of working women. Purposive sampling has been used to select four women and two men working in tech, and in-depth interviews over the telephone were conducted for a phenomenological study. Analysis of data was carried out by Interpretative Phenomenological Analysis (IPA). The results highlight common issues women face in the tech industry and compare it to their male counterparts’ experiences. Women highlight unconscious biases, internal and external obstacles, lack of women mentors at senior positions, and family restrictions. This paper gives a deeper understanding of the lived experience of entry-level men and women currently working in the tech industry, which will help identify gaps in our current approach towards inclusivity and the way forward for these practices for employees in STEM fields. The study is significant for organizations struggling to maintain gender balance in the tech industry despite implementing several diversity and inclusion practices. It will help the organizations understand a relatively new term, including inclusion and adopting specific measures to create an inclusive work environment.
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Background. Cardiovascular disease is a global emerging problem and its risk starts in children and adolescents. Adolescents have modifiable cardiovascular risk factors that have been found globally, and nationally, and early intervention programs may be able to lower these risks for both individuals and populations. Accurate risk factor evaluation at the individual level is crucial in this situation for the prevention of cardiovascular disease. Objective. The study aimed to investigate cardiovascular disease knowledge and to determine physical activity, and dietary patterns among school-going adolescents in Arakkonam, Tamil Nadu, India. Methods. A school-based cross-sectional survey was conducted to assess cardiovascular disease knowledge among 500 adolescents aged 10-18 from public schools. The study period was from September 2021 to February 2022. The measurement taken on anthropometrics such as height, weight, body mass index, and bio-physiological measurement as blood pressure, structured questionnaire assessed for knowledge, dietary questionnaire assessed previous week food consumption which the investigator developed, and physical activity standard questionnaire assessed the past week’s exercise level. Data were analyzed using IBM Statistical Package for Social Sciences version 20. Results. The mean study population age was 13.7±1.7, 53% were boys, and 47% were girls. Factors like age 16-18 years (p=0.01), site of residence from urban (p=0.001), education of teenagers (p=0.01), and family history of cardiovascular disease (p=0.001) are significantly correlated with the level of knowledge score, with better-educated adolescents having fair knowledge score than others. Level of knowledge score and demographic traits are associated with physical activity, such as 16 to 18 years (p=0.03), living in an urban region (p=0.03), being in a joint household (p=0.001), adolescents who are at higher secondary (p=0.02), and having a family history contribute more to cardiovascular disease (p=0.001) than other variables. Mean days eating diets were egg (4.18±2.27), vegetables (3.92±0.93), milk products (3.85±1.87), fried foods (3.75±1.25), toffees, and chocolates (3.35±1.81) all had higher percentages of consumed foods than others. Conclusion: There is a risk of cardiovascular disease higher among adolescents. Still a need for school-based primordial preventive educational approaches needed to improve to curb this burden.
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The study has been conducted in Animal House/Faculty of Sciences/University of Kufa between December 2022 and February 2022, fifteen female Albino Rats are used. Gentamicin is aminoglycoside antibiotics widely used during pregnancy for treatment the infections . The present study has been intended to show Alfa Feto Protein parameter in serum and the histological effects of gentamicin on pups liver by SEM in female Albino Rats. The females Rats are randomly divided into three main groups, comprising five rats for each group .The control group is given inta peritoneal injection of physiological normal saline and the second and third group are given inta peritoneal injection of gentamicin doses twenty, forty mg/kg/day respectively for 20 days from the first day to the end of experimental allocated for each female.The rats are sacrificed in 20 th (dpc) to study the Alfa Feto Protein parameter in serum and histological effects of gentamicin on pups liver. The physiological study show negative results in all study groups due to absent of malformations in pups and present histological effects in external architecture structure of pups liver compare with control groups. In conclusion aminoglycoside gentamicin caused histological effects on pupa liver and not absent of malformations in pups due to negative results of Alfa Feto Protein parameter
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A study on impact of coronavirus pandemic on the education system
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Objective: Because of the recent COVID-19 outbreak, the government decides to close the schools to avoid the virus chain. However, that made a tremendous impact on the education system. Hence, the research’s main aim focuses on the effect of the education system on the corona. Method: Research has implemented a descriptive method. Through the standardized questionnaire using the Likert scale, the data was collected via an online survey, where 300 respondents were found to be used as the sample size and regression analysis to prove the significance of the findings. Findings: The study found that obstacles act as a roadblock in the education system, while the study found resources that were also helpful to students and teachers. Practical Implication: Application of such factors by leveraging the educational sector as an opportunity could work for them if effectively applied. Students will learn something new and develop technological skills they would not have had before. Originality/Value: Researchers have studied challenges and opportunities during a pandemic situation by applying theories and analyzing the impact on the education system. The current research considers such aspects as to what effect on the education sector or how it handles the framework as a burden or as an opportunity.
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INTRODUCTION: Hemodialysis is a continuous treatment that might result in problems such as hypotension, leg muscle cramps, disequilibrium syndrome, and nausea. The most effective treatment is passive stretching of the shortened muscle. Stretching has numerous health benefits, including increasing stamina, relaxing the body and mind, improving focus and concentration, and lowering the chance of injury. OBJECTIVE: The goals of this study were to determine the severity of leg muscle cramps in Hemodialysis patients before and after intradialytic stretching exercises, to assess the effectiveness of intradialytic stretching exercises on leg muscle cramps in Hemodialysis patients, and to link the severity of leg muscle cramps with selected demographic variables following intradialytic stretching exercises. MATERIALS AND METHODS: Qualitative research approach was conducted at Saveetha Medical College and Hospital by using quasi experimental research design, the Sample size was 30 patients with leg muscle cramps undergoing Hemodialysis by using Purposive sampling technique. The muscle cramp questionnaire scale was created to determine the severity of leg muscle cramps before and after Hemodialysis. Pain Scores ranged from 0 to 10 on a numerical scale. Before the individuals were given the intradialytic stretching exercise, demographic data, clinical variables and muscle cramp status were measured as a pre-test. Then, every day after the intervention, the posttest muscle cramp was measured. RESULTS: The demographic and clinical variables data was analysed using descriptive and inferential statistics. The majority of the patients 17(56.7%) reported no pain during the post-test. There was no correlation between the severity of leg muscle cramping and any of the demographic variables. Data were categorized and analysed using descriptive (mean, percentage, and standard deviation) and inferential statistics (independent paired t test’, chi-square analysis). CONCLUSION: This study showed that regular stretching exercises on legs during the hemodialysis can help alleviate the leg muscle cramps.
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Pain is a feeling that is triggered by harmful stimuli. Osteoarthritis is a highly common ailment that is sometimes referred to as “wear and tear” of the body’s joints when pain is present. The knees, hips, hands, and spine are mostly affected joints as per the data. The cause is employment impairment now males over 50 in the United States, after ischemic heart disease, and it lead to more hospitalizations each year than rheumatoid arthritis (RA). The goal of this study was to see how much knee discomfort patients with osteoarthritis had before they did isometric exercise. The goal of this study was to see how much pain patients with osteoarthritis experienced after doing isometric exercises. To see how isometric exercise affected the level of knee soreness before the exam. to see if there’s a link between knee pain severity and various demographic characteristics A pre-experimental one-group pretest and post-test research design was adopted in this investigation. The qualitative research took place in the orthopaedic ward of Sree Balaji Medical College and Hospital in Chennai. A non-probability purposive sampling strategy was Chosen to select 60 osteoarthritis patients. The majority of the 3o samples have severe joint ache, according to preliminary findings. 15 (50) and 10 (33) percent of experienced severe ligament ache, respectively, while 5 (17) percent had slight discomfort as well as nobody had not at all ache. Previous testing revealed that the majority of the 30 samples were pain-free, with 8 (27%) and 18 (60%) having minor knee discomfort, 4 (13) percent having adequate ache, and nobody having excessive discomfort. paired ‘t’ value calculated was 20.3, suggesting that the difference between the pre- and post-test was statistically significant at P0.001. Conclusion: In the orthopaedic ward of the Sree Balaji Medical College and Hospital in Chennai, isometric exercise improves knee ache in osteoarthritis patients.
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Coronavirus has become a global emergency and has left a strong impact on people all over the world. It has altered the way we live, the way we work, and the way we see the world around us. Ever since the virus escalated and with lockdown in place, a significant change has been reported in consumer’s online buying behavior. This research aims to provide implications from a consumer’s perspective, thereby helping brands to gain insight into this vulnerable and unreal environment. This change in consumer mindset is investigated with respect to the risk and trust perceptions of online buying behavior. During a lockdown, an increased purchase with regards to non-perishable items was observed. The lockdown has brought about positive changes in consumers in terms of food wastage. To test the proposed hypothesis, data was collected from 200 respondents through an online survey. The results provided strong evidence that was independent of the pandemic. However, COVID-19 has acted as an element that made consumers opt for the online channel.
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AR, VR has introduced a new set of interfaces that can potentially transform the way humans interact with their surroundings completely. AR/VR can be used in airlines’ manufacturing, supply-chain, and pilot training to enhance the passenger experience. This research focuses on the use of VR and AR in enhancing passenger experience would affect the customer’s decision to travel through flights and, on that basis, analyze whether it is a good opportunity to invest in these technologies. Customer satisfaction is what every business targets to achieve. Moreover, the same goes for airlines too. The research scope includes both in-flight as well as terminal experience. AR/VR technologies would focus on Entertainment, Ease of use, and navigation purpose in the complex structure of airports. The methodology includes a structured interview in the form of a survey of 60 people who have traveled via flights. T-test analysis has been used to find out the significance of the above-mentioned variables. The purpose of this paper is to find out whether users prefer the use of AR/VR technology when it comes to boost their passenger experience, and based on the result to know whether it is a good investment for the airlines or not.
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Aim The aim hereof is to study the glutathione system peculiarities in the cardiac mitochondria in experimental animals against the background of a tumor process, chronic pain and the combined effect both of chronic pain and the tumor process. Materials and methods The experiment has been carried out in female mice of the C57BL / 6 line (n = 28), aged 8 weeks, with an initial body mass of 21-22 g. The animals have been divided into the following groups: an intact group as the reference (n = 7), a test group with a reproduction of the chronic pain model (n = 7), a comparison test group (B16/F10), which covered the animals with standard subcutaneously inoculated melanoma B16/F10 (n = 7), and the main experimental group (chronic pain + B16/F10) of mice with B16/F10 melanoma inoculated 3 weeks after the chronic pain model development (n = 7). All rodents have been decapitated with a guillotine upon completion of 3 weeks of the experiment (on 21 day of the experiment). After decapitation, the animal hearts have been quickly removed with the use of coolants, and mitochondria have been isolated...
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Adaptive reactions as a guideline in evaluation of metabolite therapy
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Unilateral oophorectomy (UOE) of female rats caused severe stress with an increase in the duration of the non-reproductive period (NRP) - the metestrus and diestrus phases, and a shortening of the reproductive period (RP) - the proestrus and estrus phases in the estrus cycle (a symptom of hormonal deficiency). 5 weeks after UOE, the signs of stress persisted: a decrease in the ratio of lymphocytes to the neutrophilic leukocytes in the peripheral blood and the weight ratio of thymus to the adrenal glands, as well as a decrease in the activity of succinate dehydrogenase, which is determined cytobiochemically in peripheral blood cells. A two-week administration of a succinate-containing composition with B vitamins (SCCV) to control and UOE rats increased the ratio of lymphocytes to neutrophils and weight ratio of the thymus to adrenal glands above the intact level - a sign of the “activation” state according to Garkavi and Kvakina and restored the ratio of NRP/RP. At the same time, a significant increase in SDH activity was found in animal peripheral blood lymphocytes. The study demonstrates the possibility to reverse severe stress state to the “activation” state with the help of metabolic therapy containing the combination of SCC and B-Vit.
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Adhesive phytoadaptogens geroprotectors in preventive oncology
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At the current stage of medical science development there is significant knowledge about various disorders in the tumor process (expression of oncogenes and cytokines, factors of apoptosis, drug resistance, angiogenesis, deficiency of immunoreactivity, etc.). Many of the identified features of the tumor cell are trying to be used as targets for anticancer therapy. However, it is problematic to consider these numerous “details” of the characteristics of a tumor cell as targets for anticancer therapy. This is due to the fact that they do not have a key or independent significance in the appearance of a tumor cell, although they can work in experimental animal models under certain conditions and with prolonged therapy, which at times has little relation to humans
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Age-related risk factors affecting the population morbidity
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This article analyzes age-related risk factors that affect the population health. Risk factors that contribute to poor health are those that increase the likelihood of getting sick or injured. Risk factors are often presented individually, but it is confirmed that they are often interrelated in practice. For example, physical inactivity will lead to weight gain, high blood pressure, and high cholesterol over time. Together, they significantly increase the chance of developing chronic heart and other diseases, and the older a person is, the more various factors impact his health. The study aims to identify age-related risk factors affecting the morbidity of the population. The research was carried out using theoretical methods: the study of scientific articles, literature on the topic, and practical methods: observation and generalization. As a result, it was revealed what risk factors affect the population’s morbidity, the form and degree of their influence on humans, and methods for reducing the influence of these factors were proposed.
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The Glasgow Coma Scale (GCS) is a widely used clinical tool for objectively measuring impaired consciousness in various acute medical and trauma conditions. This study aimed to explore the significance of assessing GCS knowledge among nurses. The research was conducted at PNS Shifa Hospital Karachi, situated in DHA Phase-II near Korangi Road Karachi, which provides training courses for medical professionals in the Pakistan Navy. The study employed a quantitative, descriptive crosssectional design. The findings of this study revealed that among the nurses at PNS Shifa Hospital, 63.33% possessed a high level of knowledge regarding GCS, while 35% had a moderate level, and only 1.67% had a low level of knowledge. Additionally, the study identified that nursing students at PNS Shifa Hospital exhibited varying levels of GCS knowledge, with up to 50% having a low level, 60 to 80% having a moderate level, and 80 to 100% demonstrating a high level of understanding. Furthermore, the study included demographic data indicating that out of the ttal participants, 20 were male and 40 were female nurses. In terms of age distribution, 40 nurses fell within the 20-25 years age group, while 20 nurses were between 26-30 years old. Moreover, the educational qualifications of the participants included 25 nurses with a General Nursing (GN) diploma, 2 with an advanced diploma after GN, and 38 with a Bachelor of Science in Nursing (BSN)/Post Navy and Allied Navies. This study highlights the importance of assessing GCS knowledge among nurses in the clinical setting. The findings underscore the need for targeted educational interventions to improve the understanding and application of the GCS scoring system, which serves as a crucial tool for decisionmaking and triage in assessing compromised consciousness levels.
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Aims To overcome numerous contradictions in the knowledge of the blood transportation, a hypothesis was supposed asserting the swirling pattern of blood flow in the heart and main vessels which resembles tornado-like flows and which is widespread in nature. These flows can be exhaustively described by the exact solutions of the nonstationary hydrodynamic Navier-Stokes equations and the continuity equations for the class of viscous swirling flows offered by Kiknadze - Krasnov. Materials and methods Using morphometric studies of human and canine left ventricular casts and Multislice Computed Tomography it has been shown that the trabeculae in the ventricular cavity are oriented along the streamlines of the tornado-like flow of appropriate dimension. Moreover, this principle covers both the diastolic trabeculae of the inlet part of the left ventricle and the systolic trabeculae of the outlet part of the left ventricle. Results It is concluded that the main trabeculae function consists in the structural organization of the intraventricular tornado-like swirling flow of Kiknadze – Krasnov type. Conclusion The hydrodynamic analysis of the blood flow laws is indispensable for the development of new diagnostics criteria in cardiology, cardiac surgery optimization, the design of new implantable and paracorporal devices contacting with blood flow and mathematical and physical modeling of circulation.
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Analysis of the infectious morbidity in the children's population in the city of Krasnodar
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Aim. Our aim hereof is to assess the status of infectious morbidity in the pediatric population in the territory of the Russian Federation and the City of Krasnodar in the period 2021-2022 by an example of the State Health Institution “Pediatrics Polyclinic No 2”, Department of Health Care of the City of Krasnodar. Material and Methods. Our work has been completed with use of official statistical data of the Federal Service of the state statistics of the Russian Federation, the database of Rospotrebnadzor of the Krasnodar territory, statistical data set collections of FGBI “The Central Research Institute of the Management and Information of Public Health Care” at the Ministry of Health Care of the Russian Federation. A retrospective analysis was performed using data from the State Report “The state of sanitary and epidemiological welfare of the population in the Russian Federation in 2021”. Statistical processing was carried out using GraphPad Prism 5.0 and Word Excel. Results. According to the data on the sanitary and epidemiological well-being of the population, an increase in the number of cases of infectious and parasitic diseases was recorded in the Russian Federation in 2021. The sharp rise in the incidence of infectious diseases is directly related to the spread of the new COVID-19 infection. The incidence of ARVI among children in 2021 was 68,062.49 per 100,000 that is 15.4% higher than in 2020. In Krasnodar, there were 236,332 patients diagnosed with infectious diseases in 2021. According to the data submitted by Branch No. 2 of the Krasnodar City Pediatrics Hospital at the City Health Care Department, the overall morbidity of children in the first year of life in 2022 has decreased. No cases of diphtheria, pertussis, poliomyelitis, measles, and viral hepatitis B were recorded by the outpatient clinical institution during the study period. As a part of preventive measures, children are routinely vaccinated by the Pediatrics Hospital No. 2; at the end of 2022, 98.3% of children in risk groups had been successfully treated and were allowed to be vaccinated. Conclusion. Over the period 2021-2022, there has been a decline in the incidence of diseases in children in the first year of life in the Krasnodar Region. At the same time, the recorded overall occurrence rate of acute upper respiratory tract infections of multiple and unspecified localization remains high that is due to the difficulty of diagnosing them at the early stages of infection, and, as a result, the effectiveness of their treatment is low that may be accompanied by high mortality.
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Analyzing the impact of COVID-19 on the hotel industry in Nepal
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COVID-19 pandemic has significantly affected the tourism and hospitality sectors across the globe. Due to the increase in the number of COVID positive cases, governments of countries have imposed strict lockdown globally as a precautionary measure to control the spread of the coronavirus, which has led to restrictions on travel and mobility of individuals from one place to the other. One of the countries that have been severely affected due to the lockdown is the economy of Nepal. Being a tourist-friendly nation, every year, Nepal’s tourism and hospitality sector contributes significantly to its GDP. With a restriction on travel and cancellation of bookings, one of the most important departments under this sector, the hotel industry, is currently struggling to survive due to loss of revenue. The present study tries to understand the challenges and strategies planned by the hotel industry stakeholders in Nepal. A primary survey conducted with hoteliers from 10 hotels reveals major concerns about maintaining a steady financial performance and expectations for government aid to help this sector come back to normalcy.
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Autotransplantation of a free flap of the gracilis muscle is currently actively used in reconstructive surgery for persistent prosoplegia, injuries of the brachial plexus, for plastic closure of defects in the upper lip, and in the treatment of pelvic sepsis. This study provides important information about the anatomical features of the gracilis muscle and its neurovascular bundle, which are highly variable. The study of the anatomical and topographic features of this fine thigh muscle was carried out on a sectional study of 25 corpses of both sexes, 50 lower limbs. The present study demonstrates that the median value of the total length of m. Gracilis, the length of its muscular part, as well as the length of the tendon were 452.25 (439.7; 462.0); 225.3(208.1;239.0); 230.5 (213.0; 244.4) mm, respectively. The number of vascular pedicles included in m. Gracilis, ranged from 1 to 5. In 86% of the cases, the deep femoral artery formed the dominant vascular pedicle, and in 14% of cases, it was the medial circumflex artery. Small secondary vascular pedicles originated from the descending genicular artery or the anterior branch of the obturator arter: from the basin of the internal iliac artery. The length of the main feeding artery varied from 76 to 134 mm, the median value was 100.5(90;110) mm, and its diameter ranged from 1.4 to 2.1 mm (M = 1.9(1.8;2, 0) mm. The innervation of the fine muscle of the thigh was carried out by the anterior branch of the obturator nerve, which in 82% of the cases was represented by a single trunk; less often a loose type of structure was observed. The proper nerve was located at a distance of 108.5 (96; 117) mm from the origin of the muscle; its diameter was 2.1 (1.9; 2.2) mm. Knowledge of the topographic and anatomical relationships of the neurovascular bundle with the surrounding formations, variants of its individual anatomical variability are the key to successful reconstructive surgery.
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The results obtained in this study have demonstrated a possibility to increase the efficacy of the complex treatment of patients with brain tumors of a high degree of malignancy with the use of factors of the magnetic-wave nature, including low-intensity PMF and ELF MF, which can be integrated into the adjuvant therapy scope.
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Aim. The purpose of the study was to reveal the effectiveness of the Cytochrome C drug in the early stages of the Pliss lymphosarcoma growth in white outbred rats. Material and methods. The studies were included white outbred male rats with an initial weight of 180–220 g (n = 40) with subcutaneously inoculated Pliss lymphosarcoma. Rats in the main group received the Cytochrome C intraperitoneally in a single dose of 1.6 mg/kg 1 hour after the tumor inoculation and then until death; animals with tumors in the control group received saline instead of the studied drug in the same way and in the same dosage. Results. Subcutaneous tumors appeared in the control group in 100% cases, in the main group in 55% cases; tumors were not detected in 45% of animals in the main group. In rats of the main group receiving experimental treatment, tumors regressed with time: in 73% cases with complete recovery of rats, in 27% cases animals died. Conclusions. The Cytochrome C in a therapeutic and prophylactic regimen had a pronounced antitumor effect. Perhaps the effectiveness of the drug can be improved using an inert carrier which will protect the protein from proteolytic cleavage when it enters the bloodstream, together with detoxification agents.
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