Влияние микробиоты кожи на дерматологические реакции при проведении химиотерапии

Автор: Кретова К.А., Маркина В.А., Новиков С.С., Сергеева И.Г., Филипенко М.Л., Сидоров С.В.

Журнал: Злокачественные опухоли @malignanttumors

Статья в выпуске: 3S1 т.13, 2023 года.

Бесплатный доступ

В настоящее время микробиому уделяется все больше внимания. Проводилось и проводится до сих пор множество исследований по влиянию микробиома человека на возникновение, течение различных заболеваний. В настоящее время существует теория о влиянии микробиоты кожи на возникновение кожной токсичности у онкологических больных. При проведении лекарственной терапии онкологических больных существуют различные нежелательные реакции, которые могут влиять на частоту и длительность проведения лечения. К наименее изученным можно отнести дерматологические реакции. Индуцированной химиотерапией повреждение клеток изменяет микробную среду. Но до сих пор в этой области существует пробел в знаниях о механизме дисбиоза микробиоты кожи, приводящей к кожной токсичности. Понимание микробиоты кожи и его связи с кожной токсичностью, связанной с химиотерапией, может помочь в развитии стратегического планирования и терапевтического вмешательства, повышающих качество жизни пациентов.

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Микробиом, рак молочной железы, кожная токсичность, химиотерапия

Короткий адрес: https://sciup.org/140302076

IDR: 140302076   |   DOI: 10.18027/2224-5057-2023-13-3s1-53-63

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