Повышенный уровень сыворотки гомоцистеина и действия глутатиона-С-трансферазы у пациентов с алкогольной зависимостью, посещающих наркологический центр

Автор: Кулкарни С.Р., Равиндра К.П., Дъюме С., Ратаболи П.В., Родригез Э., Родригез Э.Е.

Журнал: Саратовский научно-медицинский журнал @ssmj

Рубрика: Клиническая лабораторная диагностика

Статья в выпуске: 3 т.6, 2010 года.

Бесплатный доступ

Изучался эффект от интенсивного употребления алкоголя на сыворотку малондиалдегида, состояние гомоцистеина и активность глутатиона-с-трансферазы у алкоголиков из низкого социально-экономического слоя населения, употреблявших запрещенные (несертифицированные) спиртные напитки и посещавших наркологический центр. В исследовании участвовали 90 пациентов с алкогольной зависимостью, употреблявших запрещенные спиртные напитки и посещавших наркологический центр, и контрольная группа - 90 лиц без алкогольной зависимости. Были оценены сыворотка малондиалдегида, сыворотка гомоцистеина и активность антиоксидант-фермента глутатиона-с-трансферазы. У алкоголиков, употреблявших запрещенные спиртные напитки и посещавших наркологический центр, выявлен значительно более высокий показатель концентрации сыворотки малондиалдегида, уровня сыворотки гомоцистеина и глутатиона-с-трансферазы в сравнении с контрольной группой, принадлежащей к такому же социально-экономическому слою населения. Результаты исследования показали, что с увеличением концентрации сыворотки малондиалдегида, сыворотки гомоцистеина и активности антиоксидант-фермента глутатиона-с-трансферазы может усиливаться восприимчивость к сосудистым заболеваниям при интенсивном употреблении запрещенных спиртных напитков и при недостаточном, неполноценном питании

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Алкоголь, глутатион-с-трансфераза, гомоцистеин

Короткий адрес: https://sciup.org/14917141

IDR: 14917141

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