Perspective of gene therapy for heart failure

Автор: Malishevskiy M.V., Kukarskiy A.Y., Semukhin D.M.

Журнал: Академический журнал Западной Сибири @ajws

Рубрика: Медицина. Внутренние болезни

Статья в выпуске: 3 (64) т.12, 2016 года.

Бесплатный доступ

Короткий адрес: https://sciup.org/140220007

IDR: 140220007

Список литературы Perspective of gene therapy for heart failure

  • Engelhardt S., Hein L., Dyachenkow. V. et al. Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation//Circulation. -2004. -Vol. 109, № 9. -P. 1154-1160.
  • Milano C.A., Allen L.F., Rockman H.A. et al. Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor//Science. -1994. -Vol. 264, № 5158. -P. 582-586.
  • Hata J.A., Williams M.L., Koch W.J. Genetic manipulation of myocardial beta-adrenergic receptor activation and desensitization//J. Mol. Cell. Cardiol. -2004. -Vol. 37, № 1. -P. 11-21.
  • Shah A.S., White D.C., Emani S. et al. In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction//Circulation. -2001. -Vol. 103, № 9. -P. 1311-1316.
  • Katz M.G., Fargnoli A.S., Swain J.D. et al. AAV6-betaARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve//J. Thorac. Cardiovasc. Surg. -2011. -May. -Vol. 50, № 5. -Р. 766-776.
  • Gao M.H., Lai N.C., Roth D.M. et al. Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice//Circulation. -1999. -Vol. 99, № 12. -P. 1618-1622.
  • Lai N.C., Roth D.M., Gao M.H. et al. Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity//Circulation. -2000. -Vol. 102, № 19. -P. 2396-2401.
  • Kawase Y., Ly H.Q., Prunier F. et al. Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure//J. Am. Coll. Cardiol. -2008. -Vol. 51, № 11. -P. 1112-1119.
  • Sakata S., Lebeche D., Sakata N. et al. Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins//J. Mol. Cell. Cardiol. -2007. -Vol. 42, № 4. -P. 852-861.
  • Sakata S., Lebeche D., Sakata Y. et al. Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardio myocyte size in a type 2 diabetic rat model//Am. J. Physiol. Heart. Circ. Physiol. -2007. -Vol. 292, № 2. -P. 1204-1207.
  • Lyon A.R., Bannister M.L., Collins T. et al. SERCA2a Gene transfer decreases SR calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure//Circ. Arrhythm. Electrophysiol. -2011. -Jun. -Vol. 4, № 3. -P. 362-372.
  • Cutler M.J., Wan X., Laurita K.R. et al. Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans//Circ. Arrhythm. Electrophysiol. -2009. -Vol. 2, № 6. -P. 686-694.
  • del Monte F., Lebeche D., Guerrero J.L. et al. Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling//Proc. Natl. Acad. Sci. USA. -2004. -Vol. 101, № 15. -P. 5622-5627.
  • Prunier F., Kawase Y., Gianni D. et al. Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump over-expression in a porcine model of ischemia reperfusion//Circulation. -2008. -Vol. 118, № 6. -P. 614-624.
  • Hadri L., Bobe R., Kawase Y. et al. SERCA2a Gene Transfer Enhances eNOS Expression and Activity in Endothelial Cells//Molecular Therapy. -2010. -Jul. -Vol. 18, № 7. -P. 1284-1292.
  • del Monte F., Harding S.E., Dec G.W. et al. Targeting phospholamban by gene transfer in human heart failure//Circulation. -2002. -Vol. 105, № 8. -P.904-907.
  • Nicolaou P., Rodriguez P., Ren X. et al. et al. Inducible expression of active protein phosphatase-1 et al. inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury//Circ Res. -2009. -Apr. 24. -Vol. 104, № 8. -P. 1012-1020.
  • Pathak A., Baldwin B., Kranias E.G. Key protein alterations associated with hyperdynamic cardiac function: insights based on proteomic analysis of the protein phosphatase 1 inhibitor-1 overexpressing hearts//Hellenic J. Cardiol. -2007. -Vol. 48, № 1. -P. 30-36.
  • Pathak A., del Monte F., Zhao W. et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1//Circ. Res. -2005. -Vol. 96, № 7. -P. 756-766.
  • Most P., Pleger S.T., Volkers M. et al. Cardiac adenoviral S100A1 gene delivery rescues failing myocardium//J. of Clinical Investigation. -2004. -Vol. 114. -P. 1550-1563.
  • Pleger S.T., Most P., Boucher M. et al. Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue//Circulation. -2007. -Vol. 115, № 19. -P. 2506-2515.
  • Most P., Koch W.J. S100A1: a calcium-modulating inotropic prototype for future clinical heart failure therapy//Future Cardiol. -2007. -Vol. 3, № 1. -P. 5-11.
  • Kho C., Lee A., Jeong D. et al. SUMO1-dependent modulation of SERCA2a in heart failure//Nature. -2011. -Vol. 4, № 77 (7366). -P. 601-605.
  • Ghadge S.K., Muhlstedt S., Ozcelik C., Bader M. SDF-1alpha as a therapeutic stem cell homing factor in myocardial infarction//Pharmacol. Ther. -2011. -Vol. 129, № 1. -P. 97-108.
  • Kawase Y., Ladage D., Hajjar R.J. Rescuing the failing heart by targeted gene transfer//J. Am. Coll Cardiol. -2011. -Vol. 57, 10. -P. 1169-1180.
  • Chen J., Chemaly E., Liang L. et al. Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury//Am. J. Pathol. -2010. -Vol. 176, № 4. -P. 1705-1715.
  • LaRocca T.J., Schwarzkopf M., Altman P. et al. Beta2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4//J. Cardiovasc. Pharmacol. -2010. -Vol. 56, 5. -P. 548-559.
  • Cottage C.T., Bailey B., Fischer K.M. et al. Cardiac progenitor cell cycling stimulated by pim-1 kinase//Circ. Res. -2010. -Vol. 106, № 5. -P. 891-901.
  • Fischer K.M., Cottage C.T., Wu W. et al. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase//Circulation. -2009. -Vol. 120, № 21. -P.2077-2087.
  • Matsui T., Tao J., del Monte F. et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo//Circulation. -2001. -Vol. 104, № 3. -P. 330-335.
  • Fomicheva E.V., Turner I.I., Edwards T.G. et al. Double oxygen-sensing vector system for robust hypoxia/ischemia-regulated gene induction in cardiac muscle in vitro and in vivo//Mol. Ther. -2008. -Vol. 16, № 9. -P. 1594-1601.
  • Giuseppe Rengo, Gennaro Pagano, Pasquale Perrone Filardi, Grazia Daniela Femminella et al. Prognostic value of lymphocyte G proteincoupled receptor kinase-2 protein levels in patients with heart failure//Circ Res. -2016. -Apr. 1. -Vol. 118, № 7. -P. 1116-1124.
  • Sikkel M.B., Hayward C., MacLeod K.T., Harding S.E., Lyon A.R. SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope//Br. J. Pharmacol. -2014. -Jan. -Vol. 171, № 1. -P. 38-54.
  • Hajjar, Roger J. et al. Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure//J. of Cardiac Failure. -2008. -Vol. 14, № 5. -P. 355-367.
  • Jaski B.E., Jessup M.L., Mancini D.M. et al. Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial//J. of cardiac failure. -2009. -Vol. 15, № 3. -P.171-181.
  • Mariell Jessup, Barry Greenberg, Donna Mancini, Thomas Cappola et al. On behalf of the сalcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID) investigators background-adeno-associated virus type 1/sarcoplasmic reticulum Ca2+-ATPase was assessed in a randomized, double-blind, placebocontrolled, phase 2 study in patients with advanced heart failure//Circulation. -2011. -Vol. 124. -P. 304-313.
  • Barry Greenberg, Javed Butler et al. Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebocontrolled, phase 2b trial//Lancet. -2016. -Mar. 19. -Vol. 387 (10024). -P. 1178-1186.
Еще
Статья