Treatment of prostate cancer with HIFU therapy: perioperative patient management and early results

Objective. High-intensity ultrasound ablation (HIFU-therapy) of the prostate gland is a young but promising treatment method. For the most effective and safe therapy, it is necessary to determine the indications for its implementation by analyzing the available results.Materials and methods. The experience of treating 55 patients with localized prostate cancer is presented. The average age is 67.6±13 L, preoperative total PSA level of blood 8.341, the Gleason grade of acinar adenocarcinoma is 4-6 scores, the gland volume according to MRI is 34±20.7 cm3, the PIRADSv2-4 score is used.Results. Intraoperative complications were not recorded in any case. The number and severity of postoperative complications (acute urinary retention, stricture of the prostatic urethra, accession of lower urinary tract infections, grade I-II urinary incontinence) corresponded to the data of the world literature. The postoperative total PSA index of blood within 12 months decreased by 84.58%Conclusion. HIFU-therapy is a promising and relatively safe method for treating prostate cancer with a minimum number of possible intraoperative complications. Given the low percentage of relapses of the disease, it can be concluded that the criteria for selecting patients are correct. For the formation of the complete characteristics of the method, indications and contraindications to it, it is necessary to carry out further studies.