Coherent relations of eeg rhythms during change of functional states in adults with locally conditioned epilepsy

150 patients with locally conditioned epilepsy taking antiepileptic medications have been examined. Out of them there were 72 persons with resistant form of disease (group A) and 78 persons controlling epileptic seizures (group B). Group of comparison has included 70 patients with rare epileptic seizures without intake of anticonvulsants (group C). Interhemispheric coherence has been investigated in the state of sleep, awakenings and during functional loads. In groups A and C, increase of interhemispheric coherence within range of p-rhythm during cognitive activation has been observed. In group B, increase of interhemispheric coherence within range of A-rhythm during hyperventilation and decrease within range of p-rhythm during cognitive activation has been observed. Dynamics of interhemispheric coherence was observed in frontal zones most dependent on coordinating influences of middle brain structures.