Clinical and morphological aspects of predicting bone metastases in patients with breast cancer
Автор: Tylokova Mushtari Bakhodirovna, Amanov Akmaljon Karimjon Ugli, Subkhanov Ulugbek Zhurakulovich, Karimova Mavluda Nematovna, Yuldasheva Aziza Nodirjonovna, Esankulova Bustonoy Sobirovna, Nizamova Iqbola Bakhtir Kizi
Журнал: Re-health journal.
Рубрика: Онкология
Статья в выпуске: 4 (8), 2020 года.
Бесплатный доступ
The incidence of breast cancer is increasing worldwide. According to WHO, more than 1.4 million cases of cancer of this localization are detected annually in the world, of which almost 3000 in the Republic of Uzbekistan. Metastatic cancer is characterized by proliferation of tumor cells in various organs and tissues. In 50 to 70% of patients, already upon admission, they have advanced forms of the disease (locally widespread forms, in the form of lesions of regional lymph nodes and distant metastases to various organs). The nature and frequency of distant metastases of breast cancer are very diverse. In 40-80% of cases, breast cancer metastasizes to the bone. BC spreads to the bone in 70% of cases in the form of distant metastases. BC metastases to the spine, ribs, pelvis, and proximal limbs. These lesions are more often osteoblastic, but can be osteolytic, with poor margination, lack of matrix, and cortical destruction. Other manifestations may also include spinal compression fractures and cysts as a result of osteoarthritis caused by a tumor.
Breast cancer, ductal carcinoma, lobular carcinoma, metastasis, osteoblastic, osteolytic
Короткий адрес: https://sciup.org/14125608
IDR: 14125608 | DOI: 10.24411/2181-0443/2020-10162
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