Статьи журнала - Cardiometry
Все статьи: 527
Статья научная
Aims Basic criteria of finding the markers of the hemodynamic self-regulation mechanism on an ECG and a Rheogram are described herein. The basics of an analysis of the compensation mechanism responsible for the maintenance of the hemodynamic parameters within the norms are presented in this paper. Materials and A change in the form of an ECG phase segment reflects qualitatively the methods actual contraction performance of the respective cardiac muscle part involved. In case when the contraction of a cardiac muscle part is weak, an adjacent part undertakes the required compensation function in order to adjust the process. The causality analysis allows identifying the primary cause of a pathology which makes impossible to maintain the proper phase-related blood volumes within the norms. Results An evaluation of the hemodynamic self-regulation mechanism on the basis of the analysis of the compensation mechanism responsible for the maintenance of the hemodynamic parameters within the norms allows revealing the primary cause of the cardiovascular system pathology. Conclusion We offer an innovative methodology that is easy to use and very efficient, therefore, it can be widely applied in practice.
Бесплатно
Behavioral shift of generation X towards OTT during COVID’19 in India
Статья научная
Over-the-top (OTT) services such as Netflix, Prime Video, Disney+ Hotstar, Zee5, etc., have changed consumers’ content consumption behavior. Globalization and Digitalization have encouraged consumers to have limitless access to the Internet for information, leisure, entertainment, and social interconnectedness. The increase in the availability of high-speed Internet, the latest smartphones, and breakthroughs in technology have created great opportunities for the OTT sector, with people preferring to consume content on-the-go digitally rather than traditional media services, such as cable television. The Covid’19 pandemic has seen an increase in viewership’s and subscriptions towards these streaming platforms, with people of different age groups adapting to changing viewership trends. This study aims to understand Generation X’s behavioral shift (Age 41 to 55) towards OTT during Covid’19 in India. The literature review talks about the Generation X cohort of consumers, their behavioral habits, and attitudes towards technology. It also discusses the changing trends of online content consumption and how Covid’19 has created a spark in viewership’s towards India’s online media services. The research study aims to perform explanatory research to establish a relationship between the increase in consumption and subscriptions of OTT services in India by Generation X and the impact of Covid’19 on the same. Data will be collected from consumer’s age amongst 41 to 55 in India via survey questionnaires, and linear regression tests will be performed to test the hypotheses and establish a correlation between the dependent and independent variables.
Бесплатно
Другой
Now it is the time to consider directly the energy processes in the organism, which make an effect on the athletic performance, and not only thereon. In the organism, there is a coherent system of interactions between anaerobic and aerobic energy supply with the most active role of mitochondria.
Бесплатно
Статья научная
Objective: In this study, copper oxide nanoparticles are produced using the probiotic Saccharomyces boulardii in order to assess their biological activity. The biological method of producing nanoparticles is gaining popularity due to its benefits over chemical and physical ways of synthesis in terms of affordability and environmental friendliness. Methods: To biosynthesize CuO NPs, copper sulfate was introduced at a concentration to S. boulardii’s cellfree supernatant. Results: The color change of the reaction mixture from light to dark after 150 rpm incubation, as well as the color change and antibacterial behavior, were indicators of S. bularedii’s biosynthesis of CuO NPs. The characterization completed by UV-visible spectroscopy, Atomic force microscopy, Energy Dispersive Spectroscopy, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy, and X-ray diffraction (AFM). The CuO NP absorption spectra in the reaction mixture’s UV visible spectroscopy were (537.93 nm). The XRD showed that CuO NPs’ crystal size was (14.65 nm). The SEM was provided; the shape was uniform and spherical, and the average size (16.03 nm). EDS was used to analyze the presence of elemental CuO NPs. The CuO NPs’ three-dimensional structure was seen by the AFM, and their average diameter was (41.11 nm). The FTIR spectrum reveals a variety of functional groups that are present at various locations. Gram positive and gram negative bacteria that were isolated from diabetic foot infections were multidrug resistant (MDR), and biosynthesized CuO NPs demonstrated antibacterial action against these bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis). In the form of biofilm using a microtiter plate.
Бесплатно
Статья научная
The aim is to evaluate the physiological parameters of the efficacy of cardiac mitochondria transplantation in male mice with chronic neurogenic pain and B16/F10 melanoma growth. Materials and methods. Male mice (n=37) of the C57BL/6 line were used in the research work. The animals covered experimental groups as follows: mice with chronic neurogenic pain (CNP) + B16/F10 melanoma (n=27); mice with CNB + B16/ F10 melanoma + mitochondrial therapy (MC therapy) (n=10). Mitochondria were isolated from the heart of an intact rat with the use of differential centrifugation. An introduction of mitochondria to mice was carried out daily intraperitoneally at a dose of 3.3 mg of protein for 3 weeks. Statistical analysis of the results is carried out with the Statistica 10.0 software. Results. On day 21 (week 3) of the experiment, macroscopically in the melanoma tissue in the group of animals with MC therapy, there were 2.5 times more necrosis cases than in the group without MC therapy. During the examination of the internal organs, no metastases were detected in the animals treated with MC therapy, while in 100% of the animals without MC therapy metastases were found in the lungs and in 95% of them in the spleen. In the animals received MC therapy, there was no damage to the heart muscle in 75% of the cases, while in the group of the animals without MC therapy, the presence of lesions in the form of bruises on the surface of the heart was macroscopically detected in 100% of the animals. Conclusion. Thus, intraperitoneal transplantation of intact heart mitochondria contributed to the prevention of myocardial infarction and metastases to internal organs in the C57BL/6 male mice with B16/F10 melanoma growing against the background of chronic neurogenic pain.
Бесплатно
Biological rhythms in the living cell: tunes of the life
Статья обзорная
Offered is an overview of the author's papers in exploring an interface between biological rhythms of energy, function and biosynthesis in a nerve cell of a crayfish stretch receptor. Parameters of mitochondrion aggregation rhythms integrally determine the energy metabolism in the cell. The level and the rhythms of aggregation of granular reticulum integrally reflect the regulation of biosynthesis in the body of the neuron cell. An influence of the functional activity on biosynthesis in the neuron soma and the influence of the pulse activity of the neuron are defined by rhythms of change in rates and density of flows of energy metabolism. An enhancement of the functional activity of a neuron corresponds to an increase in the rate of flow of energy produced, and an intensification of biosynthesis is linked with augmenting the energy flux density. The time lag in changing priorities in the energy regulation of the function and biosynthesis can explain variability of biological rhythm periods in a cell, the mechanism of the cell biological clock and an adaptation to the rhythms of the environment. Rhythms features of the function, biosynthesis and energetics are determined by a harmonization between the rhythms of sol-gel transitions in the cell compartments.
Бесплатно
Biophysical phenomena in blood flow system in the process of indirect arterial pressure measurement
Статья
Бесплатно
Статья научная
Objective: Saccharomyces boulardii, a probiotic, is used in the current study’s manufacture of zinc oxide nanoparticles with the aim of assessing their biological activity. Due to its advantages over the chemical and physical techniques of synthesis in terms of affordability and environmental friendliness, the biological way of creating nanoparticles is becoming increasingly relevant. Methods: Zinc acetate was added at a dose necessary to biosynthesize ZnO NPs from S. boulardii’s cellfree supernatant (1 mM). Results: An evidence that S. bularedii was responsible for the reaction mixture’s color change from light to dark after 150 rpm of incubation was the color change and antibacterial behavior. Atomic force microscopy, scanning electron microscopy, energy dispersive spectroscopy, ultraviolet visible spectroscopy, and X-ray diffraction (XRD) all contributed to the completion of the characterisation (AFM). The spectra of the ZnO NPs produced in the reaction mixture using UV-visible spectroscopy were (343.75 nm). The XRD showed that ZnO NPs’ crystal size was (13.31 nm). The SEM was provided; the shape was uniform and spherical, and the average size (24.61 nm). EDS was used to analyze the presence of elemental ZnO NPs. ZnO NPs’ three-dimensional structure was seen using AFM, and their average diameter was (62.89 nm). The FTIR spectrum reveals a variety of functional groups that are present at various locations. Gram positive and gram negative bacteria that were isolated from diabetic foot infections were multidrug resistant (MDR), and biosynthesized ZnO NPs demonstrated antibacterial action against these bacteria. (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis). All of the studied bacterial isolates showed the ability to produce biofilms in the form of nanoparticle-treated biofilms on microtiter plates.
Бесплатно
Статья научная
Breast health is extremely important for all women. However, the breast is another region of the human body that is susceptible to cancer. Breast cancer is becoming increasingly common these days, and it is now one of the leading causes of mortality globally. According to the World Health Organization, breast cancer is the most common disease among women worldwide, claiming the lives of hundreds of thousands of women each year and impacting nations at all stages of development. In fact, it is the most common cancer in women, with a significant incidence observed among those aged 30 to 50. The goal of the World Health Organization’s Worldwide Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5 percent each year; As a result, 2.5 million breast cancer deaths will be avoided globally between 2020 and 2040. To achieve these goals, three pillars must be in place: health endorsement for early detection, suitable identification at the right time, and comprehensive breast cancer management. Because of advances in early detection and care, the incidence of women dying of breast cancer has decreased by 41% from 1989 to 2018. During that time, more than 403,000 breast cancer deaths were prevented.
Бесплатно
COVID-19 pandemic: impact and opportunities for education in India
Статья научная
The sudden breakout of COVID-19 has created a major crisis in almost every sector like Travel and Tourism, Entertainment, Sports, Corporates, Financials, Manufacturing, Education, and Service sectors. We cannot identify any sector which remained unaffected by the crisis. The magnitude of the impact may vary from sector to sector. The same happened to the Indian education system. It has faced a worldwide lockdown estimating to impact almost 320 million learners across the country. India has a robust education structure, with a huge chain of more than 1.4 million schools, 799 Universities, 39071 Colleges, and 11923 Stand Alone Institutions as per data available on the sixth report of ‘All India Survey on Higher Education on the web portal, are all affected by the pandemic situation. Our Indian education system was badly impacted due to pandemics, mostly based on traditional or classroom teaching. Though most of the school and colleges, for the benefit of students, had opted for online teaching, yet some of the low income private and government teaching institutes and students from a remote location could not opt to online teaching due to the unavailability of the internet, Laptop, Desktop or Smartphones persistent with a survey by EY-Parthenon.
Бесплатно
Статья научная
The aim of this research work is to study the cAMP level in the cardiac mitochondria and serum in the C57BL/6 strain mice of both genders under the independent melanoma B16/F10 growth versus the melanoma B16/F10 growth linked to chronic neurogenic pain (CNP). Materials and methods. Mice of strain C57BL/6 (n=336) have been grouped as follows: the intact group of the mice (♂n=21; ♀n=21), the reference group (♂n=21; ♀n=21) with the reproduced CNP model, the comparison group (♂n=63; ♀n=63) to include the mice with melanoma B16/F10, and the main test group (♂n=63; ♀n=63) to cover the mice with the melanoma growth against the CNP background. Upon expiration of 1 week, 2 and 3 weeks of the melanoma growth, in the animals of the above experimental groups the cardiac mitochondria have been isolated with the centrifugation using high-performance refrigerated centrifuge Avanti J-E, BECMAN COULTER, USA. With ELISA Kit (RayBio USA) we have determined cAMP concentrations in serum and in the cardiac mitochondria. Results. CNP has induced a decrease in the cAMP level in the cardiac mitochondria by a factor of 3,6 in the female mice only. In the animals of the comparison group the cAMP level in the heart has been increasing beginning with week 2 of the tumor growth on average by a factor of 4, while in the main test group starting from week 1 of the tumor growth it has been recorded 2-4 times higher and was depleted by the end of the experiment. As to the cAMP concentration in serum, the dynamics thereof has not been found to be in correlation with the cardiac mitochondrial data, and its concentration decrease has been recorded both in the females and the males. Conclusion. So, the changes in the cAMP concentration in the cardiac mitochondria demonstrate their gender-specific feature; the female mice as against the males have responded to an independent impact produced by CNP. As to the main test group, CNP has stimulated an increase in the cAMP level in the cardiac mitochondria 1 week earlier than it is the case with the comparison group, and it has resulted in the full cAMP depletion by the 3rd week of the experiment.
Бесплатно
Отчет
The aim of the study was to evaluate the significance of cardioeigenoscopy method for the prognosis of risks of fatal arrhythmia (the primary and secondary VF) progression in AMI individuals.The study was performed with the use of the PC-assisted hemodynamic analyzer Cardiocode. The cardio-eigenoscopy was developed as a methodology that is capable of presenting all ECG changes in the basis of eigenvectors of a covariance matrix of ECG amplitudes and providing an analysis of a spectrum of eigenvalues. The ECG analysis software is implemented as a real-time monitoring of a set of parameters that makes possible to evaluate the therapy effectiveness. The cardio-eigenoscopy method is capable of assessing the risk of progression of fatal arrhythmia events in MI patients. The major markers of the possible progression of fatal arrhythmia were identified. The cardioeigenoscopy provided the maximum expressibility of an ECG curve at any specified EVE values.
Бесплатно
Cardio-oculometric (cardio-oculographic) detection of functional states in a human individual
Другой
The cardio-oculometric detection (COD) is an integrated method aimed at studying personal preferences, individual traits and current functional states of a human individual. The method is based on the use of some cardiac markers and parameters of oculomotor activity in response to specially selected visual and audial stimuli.
Бесплатно
Cardio-oсulometric indicators of psychophysiological readiness of students to examinations
Статья
Бесплатно
Отчет
The article presents some experimental results demonstrating the suitability of using the psycho-physiological reactions recorded with the Cardiocode device and the Barrier-14 polygraph to specially selected visual stimuli in order to assess the degree of authenticity of vital goals chosen by a person as key benchmarks in the implementation of the desired future.
Бесплатно
Статья научная
The aim is to conduct a cardiometric assessment of formation of acute and late toxic disorders in experimental animals with Guerin's carcinoma during carboplatin chemotherapy against the background of L-carnitine medication
Бесплатно
Статья научная
The article presents the experimental confirmation of the hypothesis that with the cardio- and oculometric assessment of various types of visual content, it is possible to conduct a selective analysis of the stimulus material used in projective diagnostics and identify a group of images most suitable for current consultation, and it also shows that there is often an increased interest in content that symbolizes the value of rivalry and risky forms of the behavior, with a high degree of probability, will correlate with the rapid manifestation of the respondent’s dissatisfaction with various kinds of restrictions on his/her behavior.
Бесплатно
Cardiometric confirmations of psychotherapeutic effectiveness of psychological sand modeling
Статья научная
The article presents experimental confirmations of the validity of the hypothesis that the theoretical construct “subpersonality”, in addition to the psychological content, really reflects the physiological preparation of a person to provide a certain type of response. It is shown that the activation of one subpersonality instead of another one can be accompanied by significant changes in the heart rate variability, which has been estimated using the Baevsky stress index (SI). The article presents some experimental data demonstrating the possibility of using the Baevsky stress index (SI) to evaluate the effectiveness of Sandplay therapy and sand modeling as psychocorrective and training methods, ranking the elements used in them according to the strength and nature of the emotional impact on a person
Бесплатно
Статья научная
The topicality of the understanding and knowledge of the impact of the COVID-19 virus infection on the human organism is obvious. In this connection, all aspects are important: diagnostics, making decision on therapy, monitoring of the effectiveness of the administered therapy and prediction of the patient condition development. In the spring of 2020, the authors hereof obtained evidence data covering a group of patients diagnosed with the COVID-19 infection who were in the Red Zone of the inpatient treatment in one of the Moscow clinical institutions
Бесплатно
