Статьи журнала - Cardiometry
Все статьи: 527
The phonocardiographic data recording & processing system: an effective approach
Отчет
Some results obtained in recording and processing of phonocardiograms are presented herein. To process phonocardiographic signals, a cascade filtration method has been used that allows detecting tones of the cardiovascular system in the background noise. The effectiveness of the proposed processing method is demonstrated by the results of visualization.
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The problem of bleeding in the postpartum period
Статья научная
The article is devoted to the problem of bleeding in the postpartum period that remains one of the main causes of maternal mortality worldwide. The article discusses the main causes of bleeding in the postpartum period, symptoms, as well as the main methods of treatment. The article also presents methods for preventing bleeding in the postpartum period. The final part of the article is dedicated to the importance of regular medical examinations and observation of all the recommendations of medical doctors to prevent bleeding in the postpartum period.
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Тезисы
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Статья научная
Aims The aim is to study the action and effects of antitumor polychemotherapy (PCT) with Anthracyclines on the cardiovascular system performance in primary oncological patients with breast cancer (BC). Materials and methods The study involved 21 females (49.8 ± 0.5 years) diagnosed with BC. PCT has been conducted in a neoadjuvant regimen in 18 patients and in an adjuvant one with Doxorubicin (60 mg/m2) and Cyclophosphamide (600 mg/m2) in 3 patients. The cardiovascular system functional state has been evaluated during six courses of PCT with the use of the Cardiocode device. At the same time, the conditions of the cardiovascular system have been assessed before PCT and during the fourth course using EchoCG and ECG. Results and conclusions Against the background of PCT with Anthracyclines noted are the cumulative changes in the blood vessel hemodynamics as reduced blood volumes ejected from the left ventricle and the atria and as alterations in the Rheogram signal. Observed is predominance of exchange of anaerobic energy over the aerobic one, characterized by a high level of the lactate concentration and accompanied by a decrease in the oxygen concentration on course 3, an increase in the phosphocreatine level on course 4 and its decrease during courses 5 and 6 of PCT...
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The relationship between severity of coronary artery disease and mean platelet volume
Статья научная
Aims Increased MPV is a risk factor for cardiovascular diseases and can be associated with coronary artery involvement. In this study, we aimed to investigate the relationship between the severity of coronary artery disease and MPV. Materials and methods In this study, a total of 200 patients with coronary artery disease were enrolled. All patients initially underwent coronary angiography. Plasma TG, LDL, and HDL, was measured using commercial kits Integra 800TM. MPV and platelet count was determined by the Sysmex XT-2000iTM. Population were divided into three groups based on the SYNTAX score: low, moderate and high. All angiographic grading of SYNTAX was carried out by two cardiologists with blinded clinical data. After Data collection, these data were entered to SPSS22 software and were analyzed using correlation coefficient regression analysis. Results A total of 200 patients entered to the study that 43% and 57 % of patients were female and male, respectively. eighty-seven patients were diabetic and other 113 patients were not diabetic...
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The relevance of Takotsubo cardiomyopathy as a stress-induced disease
Статья научная
Takotsubo cardiomyopathy, or Takotsubo syndrome, can be quite rare found, but however the frequency of diagnosing with this disease among patients of cardiology departments is constantly growing. On the one hand, this may be due to improved diagnostics of this pathology, and on the other hand, to an increasing frequency of mental disorders in the human population and the spread of other risk factors, including drug-induced variants. The pathogenesis of the development of Takotsubo cardiomyopathy is associated with an increase in the level of catecholamines, which may be the result of a reactive sympathetic enhancement in response to external factors or be the result of taking antidepressants that can produce a similar effect. Although the diagnostics of this pathology has made significant progress, but however there is still no consensus on the strategy of treatment. This is due to the lack of large-scale randomized prospective studies that could justify one or another therapeutic approach. Basically, the efforts of medical doctors are aimed at maintaining cardiac activity, eliminating the trigger of the disease and at treating complications.
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Статья обзорная
The aim of this article is a comprehensive review of the publications during the last decade in order to evaluate current indications for cardiac resynchronization therapy (CRT) in patients with heart failure (HF) and atrial fibrillation (AF). Clinical studies show that CRT not only improves HF symptoms and quality of life but also reduces morbidity in New York Heart Association (NYHA) class III or IV patients with reduced left ventricular ejection fraction (LVEF) and wide QRS. The loss of atrioventricular synchrony and difficulty to ensure an adequate biventricular pacing worsens these patients response to CRT. According to the latest guidelines CRT should be considered for patients to reduce all-cause mortality in patients with chronic HF, QRS ≥ 120 ms and LVEF ≤ 35% who remain in NYHA functional class III/ambualtory class IV despite at least 3 months of optimal pharmacological theraphy who are expected to survive at least 1 year with good functional status, provided that biventricular pacing as close as possible to 100% can be achieved (class IIa, level B). Despite the fact that there is a general agreement on the indication for CRT in AF patients, their optimal management strategy still remains a matter of discussion.
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Статья научная
The low efficacy of ongoing conventional therapy and a significant decrease in the quality of life in patients with reconstructive plastic surgery (RPO) on the pelvic organs (PO) due to tubal-peritoneal infertility (TPI) and chronic nonspecific salpingo-oophoritis (CNSO) requires searching for new, promising methods of non-drug treatment, in particular, taking into account the regional characteristics of the Republic of North Ossetia-Alania and its natural resources. One of the main ways to increase the efficacy and intensify the treatment of this category of patients is the use of natural factors, namely, sulfide waters of the local Redant-4 deposit, which have a number of anti-inflammatory effects. Purpose of the study is to assess the role of non-drug technologies using magnetic infrared-laser therapy and balneological factors of the local deposit in the rehabilitation of the reproductive function in patients undergoing reconstructive plastic surgery due to TPI and CNSO. Material and methods. 235 women with impaired reproductive function, who underwent laparoscopic reconstructive plastic surgery on the pelvic organs (RPO on PO) due to tubal-peritoneal infertility (TPI) and CNSO, whose average age was 28 + 7 years, were examined. 2 groups were formed by the method of blind sampling: the main group consisted of 139 women with RPO on the pelvic organs due to TPI and CNSO, who, along with conventional therapy, received magnetic IR-laser therapy and had hydrogen sulfide baths; the comparison group included 96 women with RPO on PO due to TPI and CNSO, whose treatment was carried out by conventional methods of drug therapy. The conventional treatment included along with antibiotic therapy the use of ecological adaptogens (aloe, apilac), immune modulators (polyoxidonium), vitamin therapy (vitamin E 100 mg / day for 3 months and B vitamins), drugs to eliminate disorders in the intestinal and vaginal flora (antifungal agents: fluconazole, tergynan, acylact for 7-14 days). The patients of the studied groups were observed before their treatment and 1-12 months after the treatment. All patients underwent a clinical and functional examination. Statistical processing of the material was carried out using the package Statistica for Windows. Results. A control examination of patients of both groups showed a more pronounced positive effect on the course of a number of clinical symptoms in the postoperative period in the main group of patients who received magnetic IR laser therapy and had sulfide baths of the North Ossetian deposit in the complex of therapy. As a result of the physiotherapy treatment, the pain syndrome was eliminated in 107 of 139 patients (77%) who complained of pain before their treatment. A decrease in pelvic pain after the course of treatment was noted in 46 patients (33%). It should be noted that in the majority of patients 94 (68%), who received sulfide balneotherapy, a decrease in the formation of repeated adhesions of the pelvis was revealed during the procedures, the effectiveness of the regression of the adhesive process was found throughout the observation. It was detected that against the background of the proposed non-drug technology in the rehabilitation treatment of patients with RPO on PO due to TPI and CNSO, a significant increase in the effectiveness of treatment of this pathology (89%), improvement in the quality of life of patients as well as restoration of fertility has been achieved. Conclusions. The use of the method of sulfide balneotherapy in patients with RPO on PO due to TPI and CNSO allows shortening the duration of their next treatment and achieving the maintenance of positive dynamics and duration of regression of the adhesive process of the pelvis.
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The role of nutritional restriction in the pathogenesis of malignant tumors
Статья
Cancer is one of the leading causes of death in developed countries. Cancer incidence is growing, and it may be associated with longer life expectancy that leads to higher risk of cancer development. Metabolic changes are among the most important aspects of the tumor progression, which appear both in the tumor cells themselves and in the tumor microenvironment, affecting later the entire organism as a whole. Abnormal metabolism of tumor cells, including activation of aerobic glycolysis and enhancement of anabolic pathways, is important in metastasizing, medical drug resistance, and in the implementation of tumor stem cell viability programs [2]. In this context, a priority is given to studies aimed at the inhibition of enzymes of metabolic processes by small molecules or some exogenous factors. Overcoming metabolic plasticity is one of the strategic goals in anticancer therapy [3].
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The role of pacemaker algorithms in preventing atrial fibrillation progression
Статья научная
Background: Unnecessaryright ventricular (RV) pacing leads to cardiac dyssynchrony and increases the risk of developing permanent atrial fibrillation. Minimizing RV pacing by specefic algorithms decreases the AF risk. Aim and objectives: Our objective was to study the effect of pacemaker algorithms on atrial fibrillation progression. Subjects and Methods: Patients with dual chamber (group A) and single chamber (group B)pacemakers were included in the study. Patients with history of AF at the time of pacemaker implantation were not included in the study. The relation between pacemaker parameters and AF development was monitored. Result: Group A showed that RV pacing percentage had high significance for developing AF with P value P
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The role of the system of insulin-like growth factors in blood in soft tissue sarcomas
Статья
Although soft tissue sarcomas (STS) belong to a group of rare diseases of mesenchymal origin, their characteristic tendency to recurrence and high mortality necessitates the search for some prognostic bio-markers to identify patients at risk of their recurrence [1]. In this regard, the system of insulinlike growth factors (IGF) and their binding proteins (IGFBP) is of interest, since it has been established that dysregulation of the IGF system leads to the proliferation of cancer cells, migration and resistance to chemotherapy.
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Статья научная
At present, control of properties of biological membranes as targets of magnetic field applications within a living cell is the subject of considerable discussion in the scientific community. Experimental studies carried out by us demonstrate that ULF MF has an access to the most important mechanisms of tumor growth. The most likely mechanism among them is that responsible for the processes of free-radicals oxidation. Therefore, our research work was aimed at studies of influences of ULF MF on indicators of the anti-oxidation system in blood plasma and blood cells in rats in the chemically induced cancerogenesis. Our experimental studies were performed in 45 outbred albino male rats having a body mass from 160 to 180 g. The state of the anti-peroxidation protection of cell membranes was assessed by indicators of the fermentation subsystem of AOS (catalase, TPA, SOD), and the state of the non-fermentive subsystem of AOS was estimated by indicators of the concentrations of vitamins A and E in blood serum...
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Статья научная
Aims The aim of our research work was to investigate the state of the lipid peroxidation system - the antioxidant protection system (LPO-AOS) in heart tissue in rats received either Doxorubicin alone or in combination with Preductal premedication. Materials and methods Our experimental studies were carried out in mature male albino rats from outbread stocks (the cohort covered 50 animals) with an individual body mass from 150 to 160 g. The cohort included the following groups of the rats: the reference group covered 10 intact animals; group 1 (20 rats) received dosage of Doxorubicin of 2mg/kg, five times, up to a cumulative dose of 10 mg/kg; group 2 (20 animals) medicated as follows: the 5-day introduction of Preductal with dosage of 35 mg/kg followed by Doxorubicin medication according to the same schedule used in group 1. MDA, levels of the A & E vitamins, SOD and catalase activity, Total Peroxidase Activity (TPA), the ratios E/A, SOD/TPA and SOD/catalase were assessed in heart tissue...
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Статья научная
Aims The aim hereof is to study the activity of cathepsin D (CatD), alkaline phosphatase (ALP) and acid phosphatase (AP), the antitryptic activity (ATA) of acid-stable inhibitors (ASI) in rats in heart tissue and its draining lymphocytes under introduction of Doxorubicin and protection with Trimetazidine.
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Статья научная
We conducted a study of the state of intracardiac hemodynamics in elderly patients with hypertension in the Kabardino-Balkarian Republic, taking into account age, gender and geographic climatic differences.
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The state of the cardiovascular system in female students after use of different doses of caffeine
Статья научная
Our article is devoted to the study of the state of the cardiovascular system in female students after the use of different doses of caffeine. Drinking 200 mg of coffee leads to a significant increase in heart rhythm and diastolic blood pressure in girls. The maximum values of heart rate (HR) and blood pressure are reached 1 hour after caffeine intake. Thus, in this case, reported is an increase in the heart rhythm by 12.7% (P ˂ 0.05), a rise in the high blood pressure by 8.8% and that in the low blood pressure level by 12.0% (P ˂ 0.05), as compared to the respective initial values thereof. After drinking 100 mg of coffee, there are no significant changes in the indicators of the cardiovascular system performance recorded: an increase in the heart rate after 1 hour has been reported to be 9.5%, a rise in the systolic blood pressure (BPs) has reached 5.0% and that in the diastolic one (BPd) 6.4%, as compared with the values of the reference group. The use of different doses of caffeine does not lead to significant changes in the duration of the waves and segments on the electrocardiogram. 3 and 6 hours after drinking coffee, the indicators of the cardiovascular system are gradually decreasing, approaching their respective initial values.
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The state of the cardiovascular system in women during pregnancy
Статья научная
The work is devoted to the study of the impact of pregnancy on the state of the cardiovascular system in women. The process of pregnancy is accompanied by significant changes in the rhythm of the heart performance and blood pressure, and the duration of the ECG waves and segments are not significantly fluctuated. The heart rhythm, gradually increasing, reaches its maximum value of 87.3 beats per minute (P
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The study of hemodynamics in critical patients under intensive care unit conditions
Отчет
Studies of hemodynamics in critical patients under intensive care unit conditions have been a very difficult task until now [1]. There are a number of reasons for that. No instruments capable of noninvasively recording data on hemodynamics and metabolism, as well as the cardiovascular system performance, could be used. Of course it is reasonable that, according to the relevant methodology, all the data should be recorded on the 'here-and-now' basis, in real time, to enable rapid decision-making in order to save the patient's life.
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Статья научная
The article presents some results of an interdisciplinary study aimed at clarifying the conditions for the use of cardiometric and electrodermal indicators of human activity as a means of attesting to visual online content. To record personal reactions to selected visual objects, the authors use a range of tools, including computer cardiometers, portable eye trackers and polygraphs of various modifications. To achieve this goal, the authors conducted a multi-level test of Russian youth using current political symbols and images from online communities and other social media platforms. The results of the study prove the high efficiency of using cardio-oculometric detection combined with automatic recording of electrodermal activity to obtain reliable information about affective and rational-logical features of perception of visual online content. The study also extends the research understanding of the specifics of using this combination of diagnostic tools in different conditions.
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The use of cardiometry in development of self-control skills by means of game sand modeling
Статья научная
The article presents experimental evidence of the validity of our hypothesis that progress in the formation and development of self-control can be fixed by assessing heart rate variability using the calculation of the Baevsky stress index (SI). Confirmation has also been obtained that this sort of cardiometric indicators can be applied as an essential element of effective bio-feedback in the course of improving a person’s ability to control his/her own psycho-emotional state using game sand modeling techniques. It is shown that the use of cardiometry in the development of self-control skills by means of game sand modeling contributes to the systematic phased internalization of the orientation scheme by the person, which he/she needs to control his/her own psycho-emotional state. The data obtained also demonstrate that the cardiometric measurements used in the course of such training help increase the rationality and awareness of the self-regulation skills to be formed and developed, and aid in strengthening the mindset for their constructive use in everyday life.
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