Reaction of the contractile function of the heart of laboratory animals to the introduction of adreno blockers

For the first time, studies have been conducted to study the features of the reaction of the shock volume of the blood of laboratory animals exposed to various modes of motor activity with the introduction of в, а1 and a2-blockers. To study the role of different subtypes of AR and M-XP in the regulation of the pumping function of the heart of animals exposed to different modes of motor activity, euphylline (в), meditin (а2), phenylephrine (а1) were administered. Muscular training of animals was carried out by increasing in time and increasing in intensity daily swimming. Restriction of motor activity, i.e. hypokinesia for laboratory animals, was created by keeping in special pencil cells. To determine the stroke volume of blood, the method of tetrapolar thoracic rheography was used. It was found that the mode of limited motor activity, i.e. hypokinesia causes a more pronounced reaction of UOC to the introduction of в and a1-adreno blockers and a less pronounced reaction to the introduction of a2-adrenoblocker. It was revealed that the regime of systematic muscle training, on the contrary, contributes to a less pronounced reaction of UOC to the introduction of в and a1-adreno-blockers and a more pronounced reaction to the introduction of an a2-adrenergic blocker.