The design of optical sensor element for microfluidic chips based on the borosilicate porous glasses

The work on chemical protein immobilization on the borosilicate porous glass was presented. Transmittance and fluorescence spectra of porous glasses at different stages of protein immobilization and after immune reaction have been measured. Images of porous glass surface were received by scanning near-field optical microscopy. The influence of drying regime between surface activation and silanization stages has been studied. The influence of silanization on protein immobilization was compared with the use of toluene and acetone. It was shown that the immune reaction results in the change of glass optical characteristics. The principal opportunity of the microsensor element production on the base of borosilicate porous glass was presented.