Signs of immunopathological processes at children, living in the territory with high technogenic loading

Children of 4-7 years, living at the territory of chemical pollution (n=28) and almost healthy children of the corresponding age (control group, n=18) are surveyed. In pathology structure at children, living at ecologically unsuccessful territory, it was prevailed the connective tissue dysplasia, on the phone of which various manifestations of transitional immunopathological processes were observed. Increase in frequency of positive results at definition of anti-nuclear factor at children from ecologically unsuccessful territory is revealed, the quantity of regulatory T-cells (CD4+CD25+CD127 low/neg) at them didn't differ from control, but the quantity of CD4+CD25+CD127+ lymphocytes that can testify the activation of immune system and risk of development of autoimmune pathology was increased.