Experience of introduction in clinical practice of non-invasive prenatal methods diagnostics of fetal gender and rhesus factor status at early stages of gestation on maternal peripheral blood

This study was aimed at identifying the reliability, sensitivity and specificity of non-invasive diagnostic methods of sex determination and Rhesus factor fetus at an early stage of pregnancy, based on the analysis of fetal DNA in a pregnant woman's blood. This study includes the results of five years of experience implementing the scientific development of «TestGen» on the Ulyanovsk Regional Clinical Hospital. Just study involved 138 pregnant women, all patients were tested extracellular fetal DNA to identify gene RHD, all women do in this case is Rh-negative. 35 and women were analyzed to establish a non-invasive prenatal fetal sex. According to the results of the study, it was found that these techniques of prenatal diagnosis of sex and Rhesus factor fetus are easy, simple and reliable method with high sensitivity and specificity already in the 10th week of pregnancy.