Experimental-and-morphological study of the effect of calcium phosphate compounds and non-collagen bone proteins upon the reparative process in bone tissue

Composite implantation material, which consists of a calcium phosphate compound and the non-collagen proteins, isolated from bone tissue and having No affinity to ion exchangers, was implanted into tibial metaphyses of 10 dogs. The stimulating effect of the composite material developed on bone tissue regeneration in the zone of metaphysis has been established. The filling of defects was based on direct osteogenesis.