Heterogenenous expression of markers associated with invasive breast cancer

Автор: Krakhmal N.V., Vtorushin Sergey V., Perelmuter V.M., Zavyalova Marina V., Slonimskaya E.M., Denisov E.V.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Лабораторные и экспериментальные исследования

Статья в выпуске: 4 (76), 2016 года.

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The paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed a number of markers related to invasive tumor growth, characterized by a pronounced heterogeneous expression pattern in all cases. Study of the expression of markers associated with invasive breast carcinoma showed that not all cells are able to promote invasive growth in different periods of time, but the fact of detecting the positive expression of the markers in tissue tumors indicates a more aggressive cancer phenotype with a high potential for invasion.

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Heterogeneous expression, invasion, breast cancer

Короткий адрес: https://sciup.org/14056791

IDR: 14056791   |   DOI: 10.21294/1814-4861-2016-15-4-56-61

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