Abstract. Рубрика в журнале - Cardiometry
Anatomy and physiology of the sinoatrial node: modern concepts
Статья
Deciding to discuss the above topic is determined due to a number of reasons. Firstly, the currently used ablation techniques make possible to reach the area of the sinoatrial (SA) node that required an accurate description of the node localization and possible ways of carrying out ablation procedures. Elucidation of SA node anatomical features in a human will allow solving the problem of the multifocal activation of atria and, as a sequence, the ablation of intranodal reentrant tachycardia. Secondly, over the last decade some disputes on the cardiac pacemaking mechanisms do not end in many international journals. Probably it is high time to submit this issue for discussion by our Russian national community of electrophysiology experts. Recent reports by Lakatta E.G. and Maltsev V.A. have significantly improved the model according to the Di Francesco’s membrane theory. Finally, the latest studies demonstrate that beating rate is controlled, in part, by local Ca2+ releases (LCRs) that creates a Rhythmic Ca2+ Clock in cardiac pacemaker cells...
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