Lipid composition of cellular membranes under Bifidum-bag probiotic in gentamicin-associated dysbiosis

Автор: Korolev Vladimir Anatolevich, Medvedeva Olga Anatolevna, Bogomazov Aleksey Dmitrievich, Verevkina Natalya Andreevna, Korolev Ivan Vladimirovich

Журнал: Ульяновский медико-биологический журнал @medbio-ulsu

Рубрика: Клиническая медицина

Статья в выпуске: 4, 2019 года.

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The erythrocyte membrane is a user-friendly model, since its structural is similar to that of molecular structure of plasma membranes. Therefore, the slightly corrected patterns of changes in the structure and functions of the erythrocyte membrane can be transferred to other membrane systems. Changes in the structure of membrane lipids under various factors are of great importance for the functional state of both the membranes themselves and the body as a whole. In diseases with severe hypoxic syndrome, changes in the membrane structure are the most obvious ones. These disorders can be observed under exposure to various drugs, namely, broad-spectrum antibiotics. The aim of the paper is to study the lipid composition of erythrocyte membranes under gentamicin-associated dysbiosis and to correct it with the B. Bifidum. Materials and Methods. The study was conducted on 60 BALB/c mice (18-20 g.). The animals were divided into three groups, 20 animals in each. The first group is a control one (intact mice)...

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Dysbiosis, phospholipids, neutral lipids, erythrocyte membrane, bifidum bag

Короткий адрес: https://sciup.org/14116399

IDR: 14116399   |   DOI: 10.34014/2227-1848-2019-4-25-32

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