Carriers of the Arg223Gln polymorphism of LEPR gene in schizophrenia patients in Trans-Baikal krai

The paper describes findings of the study of the polymorphic variant Arg/Gln LEPR gene carriers in schizophrenia patients in Trans-Baikal Krai. The study included 80 first episode schizophrenia patients. Blood samples from all patients were investigated with use of molecular-genetic analysis. It was revealed that risk for developing schizophrenia in the Gln/Gln genotype carriers was 4.33. It was found that there were gender differences: women had a greater risk than men.