With vegeto-sensory polyneuropathy during medical rehabilitation

The purpose of the work is to assess the severity of metabolic intoxication syndrome in patients with nonalcoholic steatohepatitis (NASH) and underlying pneumoconiosis with vegeto-sensory polyneuropathy (VSP) during medical rehabilitation. Materials and Methods. The authors examined 112 men, 30-59 years of age, with NASH and underlying pneumoconiosis associated with VSP. The patients were divided into two groups. The main group included 57 patients who were administered a combination of hepatrin and bronchomunal as medical rehabilitation; control group consisted of 55 patients under widely accepted NASH treatment. Nikolaychik method was used to determine the concentration of medium-weight molecules in the peripheral blood, before and after medical rehabilitation. Results. It is established that in patients with NASH and underlying pneumoconiosis with VSP there is a significant increase in the concentration of medium-weight molecules in blood serum. A comprehensive scheme of medical rehabilitation of patients with this comorbid pathology reduces the level of such molecules. However, the decrease it is not enough effective and rapid. Conclusions. Introduction of the combination of hepatoprotector hepatrin and bronchomunal immunomodulator in medical rehabilitation of patients with NASH and pneumoconiosis with VSP contributes to the everlast elimination of metabolic intoxication.