COVID-19 и сопутствующая онкологическая патология: терапевтические возможности и сложности

Автор: Патания А.С., Пратипати Ф., Абдул Б.А.А., Чава Ш., Катта С.С., Гупта С.К., Гангула П.Р., Пандей М.К., Дерден Д.Л., Байраредди С.Н., Чаллагундла К.Б.

Журнал: Juvenis scientia @jscientia

Рубрика: Переводные статьи

Статья в выпуске: 6 т.7, 2021 года.

Бесплатный доступ

Коронавирусная инфекция 2019 года (COVID-19) - это вирусное заболевание, вызываемое новым коронавирусом тяжелого острого респираторного синдрома, SARS-CoV-2, который поражает легкие инфицированных лиц. COVID-19 распространяется от человека к человеку посредством респираторных капель, выделяющихся при кашле или чихании инфицированного. Эпидемия COVID-19 началась в городе Ухань (Китай) в конце 2019 года. По состоянию на 29 сентября 2020 года более 235 стран, районов или территорий по всему миру сообщили в общей сложности о 33 441 919 подтвержденных случаях заболевания и о 1 003 497 подтвержденных смертях от COVID-19. Риску заражения подвержены люди любого возраста, но в большинстве случаев тяжелое течение заболевания наблюдается у людей старшей возрастной группы и при наличии сопутствующей патологии, которая снижает иммунитет, например, онкологических заболеваний. Данные многочисленных исследований позволяют предполагать, что пациенты со злокачественными новообразованиями могут быть подвержены более высокому риску тяжелого течения COVID-19 и летального исхода. Поэтому оказание онкологической помощи в условиях пандемии является сложной задачей и требует совместного междисциплинарного подхода для оптимального лечения онкологических больных в условиях стационара. В этом расширенном обзоре мы обсуждаем влияние пандемии COVID-19 на онкологических больных и оказание им медицинской помощи. Помимо этого, обзор содержит общие сведения о пандемии, вызванной SARS-CoV-2, характеристику генома вируса, описание патофизиологии COVID-19 и связанных с ней сигнальных путей, играющих важную роль при онкопатологии, а также информацию о вариантах использования противоопухолевых средств для лечения COVID-19.

Еще

Covid-19, коронавирусы, sars-cov-2, онкологические заболевания, воспаление, сопутствующая патология

Короткий адрес: https://readera.org/14123689

IDR: 14123689   |   DOI: 10.32415/jscientia_2021_7_6_28-70

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