Антикоагулянтная терапия при хронической болезни почек и фибрилляции предсердий: ось вращения между полюсами риска

Автор: Кобалава Жанна Давидовна, Шаваров Андрей Анатольевич

Журнал: Евразийский кардиологический журнал @eurasian-cardiology-journal

Рубрика: Обзор

Статья в выпуске: 2, 2018 года.

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Частая коморбидность фибрилляции предсердий (ФП) и хронической болезни почек (ХБП) в общей популяции продемонстрирована во многих эпидемиологических исследованиях. Большинству пациентов c установленным диагнозом ФП рекомендована постоянная антикоагулянтная терапии (АКТ) с целью профилактики ишемического инсульта и тромбоэмболических осложнений (ТЭО). При дисфункции почек на всех стадиях ХБП наблюдаются изменения в системе гемостаза, связанные как с повышением протромбогенной активности, так и развитием коагулопатии, увеличивающей угрозу кровотечения. Поэтому у пациентов с ХБП и ФП важным аспектом АКТ является выбор оптимального антикоагулянта, обеспечивающего баланс между рисками инсульта и геморрагических осложнений, чему и посвящена данная статья.

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Фибрилляция предсердий, хроническая болезнь почек, антикоагулянты, варфарин-индуцированная нефропатия, дабигатран

Короткий адрес: https://sciup.org/143165162

IDR: 143165162

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